Sex steroid hormones and systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Sex Hormones and Peripheral White Blood Cell Subsets in Systemic Lupus Erythematosus Patients
Background: Systemic Lupus Eyrythematosus (SLE) is an autoimmune disease charac-terized by antibodies to nuclear antigens, particularly anti-dsDNA. Imbalance between production and destruction of immune cells causes cytopenia. Sex hormones have im-munomodulatory effects; estrogen increases the production of autoantibodies in SLE prone NZB/NZW mice. Objective: To investigate the relationship bet...
متن کاملSex hormones in the pathogenesis of systemic lupus erythematosus.
Sex hormones--estrogens, progestins, androgens, and prolactin--have well-documented effects on the development, progression, or severity of systemic lupus erythematosus (SLE). These effects are complex and are confounded by in vitro and in vivo considerations that obscure a simple explanation of the sexual dichotomies in SLE. An overview of available experimental and clinical data suggests that...
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Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...
متن کاملsex hormones and peripheral white blood cell subsets in systemic lupus erythematosus patients
background: systemic lupus eyrythematosus (sle) is an autoimmune disease charac-terized by antibodies to nuclear antigens, particularly anti-dsdna. imbalance between production and destruction of immune cells causes cytopenia. sex hormones have im-munomodulatory effects; estrogen increases the production of autoantibodies in sle prone nzb/nzw mice. objective: to investigate the relationship bet...
متن کاملA Case of Systemic Lupus Erythematosus
SUMMARY During the course of systemic lupus erythematosus in a 10 year-old girl, a go it er develo ped. Subc linical I ly pothyrnic.Jism was found, in addition rising titer of ant imicrosomal antibody and overt hypothyroidism after 6-week cessation of thyroxin tablet lead to the diagnosis of Hashimoto's thyroiditis. Antibodies directed to the thyroid may result in an autoimmune thyroiditis in...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1981
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780240811